Londoners living in the borough of Greenwich are the most miserable in the capital, new research has revealed.
The south-east London borough was ranked the unhappiest, according to figures released by the Office for National Statistics (ONS).
Lambeth was second, while Islington was third, Haringey fourth and Croydon fifth.
Redbridge was ranked the happiest borough to live in, followed by Richmond-upon-Thames and Newham.
The data provides a half-decade picture of Britain's changing wellbeing levels for the first time and lays bare parts of the country which are the happiest, most miserable, anxious or have the highest and lowest levels of life satisfaction.
Figures showed those living in rural areas feel most satisfied with life while people in London report the highest levels of anxiety.
The top three boroughs for anxiety levels in the whole country were Hammersmith and Fulham, Sutton and Greenwich.
London also ranked lower than the rest of the country for satisfaction and finding their lives worthwhile.
A large sample of UK adults aged over 16 answered the ONS annual population survey and were asked questions, rating their answers on a scale between zero ("not at all") and 10 ("completely").
The study analysed personal wellbeing on a local level over the last five years, with respondents required to answer questions by researchers which were then used to measure aggregate levels of life satisfaction, happiness, unhappiness, anxiety and feeling worthwhile.
Across the rest of the UK, the people of Chorley in Lancashire returned the lowest levels of overall happiness with an average of seven out of 10 while those in Stirling, central Scotland, ranked highest at 8.1.
ONS statistician Dawn Snape said: "We have seen personal well-being improving on a UK-wide basis over the past five years.
"But today's data paints a richer picture, enabling people to explore what's been happening in their local area.
"This will help individuals, communities and local authorities to look at well-being locally alongside other traditional measures of progress."
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