Salt substitute ‘could prevent thousands of strokes and heart attacks’

A study of 20,995 people in rural China involved participants who had a history of stroke or were 60 and over with high blood pressure.
New research suggests thousands of strokes and heart attacks could be prevented annually in the UK if diners were to replace salt with a common substitute (Anthony Devlin/PA)
PA Archive
Benjamin Cooper30 August 2021

Thousands of strokes and heart attacks could be prevented annually in the UK if diners were to replace salt with a common substitute, new research suggests.

A study of 20,995 people in rural China involved participants who had a history of stroke or were 60 and over with high blood pressure.

Those taking part either used a salt substitute (75% sodium chloride and 25% potassium chloride by mass), or continued to consume regular salt (100% sodium chloride).

There were 29.14 events per 1,000 person-years of stroke for those taking the substitute versus 33.65 events for those eating regular salt, according to the findings, published in the New England Journal of Medicine.

In the case of heart attacks, there were 49.09 events per 1,000 person-years among those consuming the substitute as opposed to 56.29 events for salt-eaters.

And the rates of death for substitute-consumers versus salt-takers were 39.28 and 44.61 events respectively.

The study’s authors concluded: “Among persons who had a history of stroke or were 60 years of age or older and had high blood pressure, the rates of stroke, major cardiovascular events, and death from any cause were lower with the salt substitute than with regular salt.”

Professor Bruce Neal, of the George Institute for Global Health in Sydney who led the study, said in comments carried by the Times: “If you were to replace all of the salt on the supermarket shelves (in the UK) with salt substitutes, you would prevent thousands of strokes and heart attacks every year – that’s quite safe to say.”

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