A quarter of GPs believe the flu jab is unnecessary, according to a new poll.
Almost three-quarters are also against plans to extend the number of people eligible for vaccination, it found.
Of the 310 doctors questioned by GP magazine, 25.3% said influenza immunisation was not needed.
The Government's annual flu vaccination programme offers the jab to anyone over 65 and to people with chest problems and low immunity. The programme for England costs around £115m annually.
the poll found that 72% of GPs were against plans to extend the flu jab programme to adults aged 50 to 65 and children under the age of two.
Three-quarters (77%) also said they had seen no increase in the number of patients coming forward for a flu jab this flu season compared with 2006/07.
Dr George Kassianos, immunisation spokesman for the Royal College of GPs, told GP newspaper: "Evidence shows that the flu jab is beneficial but we do not give it to enough people.
"If you do not vaccinate enough people then it is not as effective.
"By extending the programme to include people aged 50 to 65 and children we can reduce the chances of the virus circulating in the community."
Dr Kassianos blamed the GP backlash against the flu vaccine on findings from a Health Protection Agency (HPA) study in November which suggested that flu jabs did not reduce hospital admissions from respiratory infections.
