Some 2.89 per cent of the capital’s population – an estimated 260,000 people – is thought to have had the virus between January 10 and January 10.
It marks a fall from two weeks ago, when one in 30 Londoners were estimated to be infected.
The ONS estimates that around one in 40 people in north-east England had Covid-19 between January 10 and 16, with one in 50 in north-west England and the West Midlands.
The other estimates are one in 55 people in south-east England, one in 60 in the East Midlands, one in 75 in eastern England, one in 80 in south-west England and one in 85 in Yorkshire and the Humber.
An estimated one in 55 people in private households in England had Covid-19 between January 10 and 16. This is the equivalent of 1.02 million people, or 1.88 per cent of the population.
This compares with an estimated one in 50 people, or 1.12 million, for the period December 27 2020 to January 2 2021.
In Wales, around one in 70 people had Covid-19 between January 10 and 16 – unchanged from the previous ONS estimate for December 27 to January 2.
In Northern Ireland the ONS estimates around one in 60 people had Covid-19 between January 10 and 16, up from one in 200 for December 27 to January 2.
The estimate for Scotland is broadly unchanged, up slightly from around one in 115 people for December 25 to 31 to one in 100 for January 10 to 16.
All figures are for people in private households - excluding care homes and hospitals.
It comes as Prime Minister Boris Johnson is set to hold a Downing Street press conference at 5pm.
He will discuss the vaccine rollout, which has seen two million doses delivered in one week.
However, the Government has come under fire for its strategy of only administering one dose per patient. Medical experts have warned that this may not be enough to protect recioients from the virus.
