A Muslim version of Live 8 will be staged to highlight the humanitarian crisis in Darfur.
Organisers are expecting more than 10,000 British Muslims at London's Wembley Arena for the charity concert.
Prime Minister Gordon Brown has lent his support, saying in a video message to be screened at the event: "I want to thank all of you who have been active on this issue, from the artists and musicians who are performing here today, to religious leaders from all communities who have been leading prayers and campaigns for the people of Darfur."
The Prime Minister continued: "The fact that so many of you are here tonight shows how deeply people from communities all over Britain care about the people of Darfur and their plight.
"An injustice anywhere is an attack on justice everywhere and so we will continue working together with all of you to bring this suffering to an end."
It is hoped the concert will raise £2 million for those displaced in Darfur.
The headlining act is singer Sami Yusuf, whose last album sold four million copies. His latest song, Asma Allah, is a recitation of the 99 names of Allah.
He was part of a Foreign Office-backed Muslim delegation which travelled to Darfur to talk to victims of the violence, refugees, tribal leaders and government officials.
Other artists on the lineup include Kareem Salama, America's only Muslim country and western singer, and Outlandish, an award-winning multi-faith hip-hop group from Denmark.
