Sara Cox will succeed Simon Mayo and Jo Whiley as the new host of BBC Radio 2 Drivetime.
This announcement comes after Mr Mayo said he would be quitting the station.
He was the voice of Drivetime for eight years but stated he would be leaving to focus on writing.
Ms Cox had been the favourite to become the new presenter following the revelation of Mr Mayo stepping down.
On taking over the slot, she said: "I've been proud to be part of the Radio 2 family for a few years now and the opportunity to present such a big show as Drivetime - playing fantastic music and hopefully making people smile as they cook tea or head home after a day's graft - is the icing on what is already a very brilliant cake.
"I'm beyond chuffed to be given this role and to directly quote my mum on hearing the good news, it is indeed 'fandabbyruddydozy'.”
The BBC have not yet announced when she will begin presenting Drivetime.
The host has experience on the station, most recently as a stand-in presenter on the Breakfast Show.
She joined the BBC in 1999 and worked on Radio 1's Breakfast Show.
The change comes just months after Mr Mayo began presenting the show with Jo Whiley.
There was consternation from some audience members when the Drivetime show was reformatted.
He defended his soon-to-be former co-host online saying: "I've loved working with the exceptional Jo Whiley and when the show was 'reconfigured' she was my first and only choice."
He added in another Twitter post: "Support for a show is one thing, assaulting the dignity of a warm-hearted and loyal friend is another."
However, Ms Whiley will not remain on the show and will be launching a new show from 7-9pm, Monday to Thursday.
Lewis Carnie, the head of Radio 2, said: "Sara is hugely popular with the Radio 2 audience and I have every confidence that she'll make the new Drivetime show her very own."
In another shake-up to the radio schedule, Trevor Nelson will be moved from his 8-10pm Saturday night slot.
Instead he will present from 10pm to midnight from Monday to Thursday.
He said: "To present eight hours a week of the music I love on BBC Radio 2 is a dream come true for me."
The host will also continue to present on BBC Radio 1 Xtra.
