Two teenagers have died following a crash between a car and their school bus.
The driver of the car also died in the collision on the A66 near Keswick in Cumbria.
The teenagers - a girl and a boy - were on their way home from Keswick High School at the time. Around 30 children were travelling on the 49-seater vehicle.
A Cumbria Police spokesman said: "Police can confirm that, tragically, two teenage children (one male, one female) who were on the school bus and the adult male driver of the Honda Civic died in the collision."
Thirty-five others were injured in the accident, which happened just before 3.47pm on Monday, police said. The bus was on a daily run carrying children from Keswick High School to their homes in Cockermouth around 13 miles away.
Barry Pickthall, who runs coach firm JB Pickthall, said the 49-seater involved was from his company and had around 30 pupils on board.
The A66 was closed while emergency services dealt with the scene.
A spokeswoman for North Cumbria University Hospitals NHS Trust said the majority of those injured in the crash were being treated at Cumberland Infirmary in Carlisle and West Cumberland Hospital in Whitehaven. She could not give any details about the ages and gender of those involved.
Meanwhile paramedics and doctors assessed the injuries of the walking wounded, which ranged from minor cuts to fractures and spinal injuries.
Cumbria Police said an information line has been set up for concerned parents and guardians to call, on 0800 096 1233 or 0207 158 0197.
