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Liverpool boss Brendan Rodgers made three changes to the side which faced Blackburn in the FA Cup as they returned to Premier League action on Monday night.
Mamadou Sakho, Joe Allen and Alberto Moreno came in for the trip to Liberty Stadium as Glenn Johnson, Dejan Lovren and Lazar Markovic dropped to the bench.
Captain Steven Gerrard was named among the substitutes as he took his place in the squad for the first time since victory over Tottenham Hotspur in early February.
Swansea: Fabianski, Naughton, Amat, Williams, Taylor, Ki, Cork, Shelvey, Sigurdsson, Gomis, Routledge.
Subs: Britton, Emnes, Dyer, Nelson Oliveira, Montero, Rangel, Tremmel.
Liverpool: Mignolet, Can, Skrtel, Sakho, Allen, Henderson, Lallana, Moreno, Coutinho, Sterling, Sturridge.
Subs: Jones, Johnson, Toure, Lovren, Gerrard, Lambert, Markovic.
Ahead of the game, Rodgers said fatigue will not hamper Liverpool's bid for a top-four place despite an arduous season so far.
"Our last performance against Blackburn was at the end of a real tough period of games," said the manager.
"I've seen all the numbers and all the statistics on it and, physically, it was the lowest we have been for this season.
"Now we're re-energised and refreshed mentally and physically.
"We go into a run of games now, starting with Swansea, and we feel we can go in and push on in terms of our level of performance again. We know it will be tough.
"It's that period of the season where you taper your training. You don't need to be as long in your training and preparation as the players have got a real good level of fitness, so it's more explosive and more intensive, but in shorter blocks.
"The players have been brilliant this week. They're looking really sharp, looking really confident and we just want to continue with our sequence of performances and good results."
